Concepts in cancer chemoprevention research
نویسندگان
چکیده
منابع مشابه
Key statistical concepts in cancer research.
In this article, we provide a high-level overview of statistical concepts related to study design and data analysis in oncology research. These concepts are discussed for 2 main types of clinical research: (1) observational studies, which focus on biomarker discovery in order to predict disease risk and prognosis, and (2) prospectively designed, well-controlled clinical trials, which are critic...
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The role of mathematics in cancer research is not confined to epidemiology (population level). The expected contribution of it in various levels is exemplified stepwise. At the individual level, prediction of life expectancy of a cancer case or psychological analysis of life-threatened patient; at the tissue level, stochastic estimation of future metastases; at the cellular level, model contruc...
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Cancer chemoprevention can be defined as prevention of cancer by the administration of one or more chemical entities, either as individual drugs or as naturally occurring constituents of the diet. Based largely on the time period that chemopreventive agents exhibit activity in animal models of carcinogenesis, they can be classified as inhibitors of carcinogen formation, blocking agents, and sup...
متن کاملCancer Chemoprevention
1Biology Department, College of Science, UAE University, Al-Ain 17551, UAE 2Zoology Department, Faculty of Science, Cairo University, Cairo 12613, Egypt 3Department for Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna Pot 111, Ljubljana, Slovenia 4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA 5Experimental Tum...
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Although uncontrolled proliferation is a distinguishing property of a tumor as a whole, the individual cells that make up the tumor exhibit considerable variation in many properties, including morphology, proliferation kinetics, and the ability to initiate tumor growth in transplant assays. Understanding the molecular and cellular basis of this heterogeneity has important implications in the de...
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ژورنال
عنوان ژورنال: Cancer
سال: 1990
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19900401)65:7<1483::aid-cncr2820650706>3.0.co;2-e